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Запой сопровождается накоплением продуктов распада этанола и нарушением работы нервной, сердечно-сосудистой и пищеварительной систем. Выведение алкоголя и стабилизация водно-солевого баланса должны проходить с учетом возраста, стажа употребления и сопутствующих заболеваний. Самостоятельное лечение после длительного запоя может быть опасным, поскольку синдром отмены иногда усиливается в течение первых суток.
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Схема помощи зависит от состояния, стажа употребления, противопоказаний и дальнейших целей лечения.
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После нескольких дней постоянного употребления организм адаптируется к присутствию этанола. Резкий отказ способен вызвать усиление абстиненции, судороги, психические расстройства и делирий. Поэтому снятие запоя должно учитывать его длительность, количество спиртного, возраст пациента и историю заболеваний. Самолечение успокоительными или лекарственной смесью без назначения врача увеличивает риск нежелательных реакций.
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